Assessment of health risks caused by overweight in children depending on the FTO gene rs9939609 polymorphism

In this study, we aimed to estimate the association between rs9939609 FTO (fat mass and obesity associated) polymorphism a risk of overweight in children living Baikal region. We performed case – control study that included 113 schoolchildren industrial centers region (Irkutsk, Angarsk, Ulan-Ude). Anthropometric parameters were measured body index was calculated with its values being ranked accordance WHO BMI curves depending on sex age. Genotyping by allele-specific amplification real-time results detection. To assess likelihood an gene allele obesity, relative (RR) 95 % confidence interval (CI) calculated. The assessment revealed A be 1.29 times more frequent examined (48.44 %) than form reference group (37.65 %). authentically associated elevated risks homozygous AA genotype (RR = 2.806, CI: 1.650–4.772; STD 0.271). Our confirms is factor for from who have genotype. Prevailing frequency TT (29.2 as compared (10.62) likely due influence assimilation processes urbanized territories